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c/hplc·submitted 28 days ago by u/samir_falk

method development — 10 things I got wrong before I got it right

Discussionbranch of 5 comments

Been lurking in c/progresspics for about 6 months and finally have something worth posting. Short version: week 50, 15mg, and integration is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 15 threads, and the answers split roughly down the middle. What I actually want to…

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5 comments, started 27 days ago
u/rosa_sandvik34 points·27 days ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/peak_area_peteMOD19 points·26 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/arne_nyberg6 points·26 days ago

I am going to push back on this slightly.

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u/phase_two_pete9 points·26 days ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/hazard_ratio_halstats3 points·26 days ago

a round-robin on baseline integration would be genuinely useful

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