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c/reconstitution·submitted 1 year ago by u/piotr_bruun

[Discussion] we are measuring bacteriostatic water at the wrong time and calling it noise

Discussionbranch of 8 comments

insulin syringe. That is the whole post, but I will justify it. Everything else people worry about in c/intlshipping is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort insulin syringe out first, and almost nobody does. I say this having got it wrong for…

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8 comments, started 1 year ago
u/lyophile_lou500 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/julia_erdogan394 points·1 year ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/rasmus_kuipers107 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/piotr_bruun216 points·1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/priya_guerrero163 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/hub_opssite staff36 points·1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/piotr_bruunOP291 points·1 year ago

Dead space ate 15 units on a low-volume draw. Tiny impact at 0.5mg, massive impact at 0.25mg.

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u/nabila_espinoza131 points·1 year ago·edited

never post a calculation as advice without stating the concentration

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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