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c/reconstitution·posted 1 year ago by u/mateusz_achebe

anyone else notice units kicking in around week 20

Correction Clean Column ×3

reconstitution. That is the whole post, but I will justify it.

Everything else people worry about in c/intlshipping is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort reconstitution out first, and almost nobody does.

I say this having got it wrong for 23 months. My ApoB was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

786 up / 234 down77% upvoted10 commentsid 16vtbg15 Feb 2025

10 comments

8 in this archive, depth 4

best — the order this archive was captured in

u/julia_erdogan71 points·1 year ago·edited

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/saskia_mwangi49 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/kavya_radich13 points·1 year ago

This is correct. 2mL versus 8mL is the common mistake.

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u/vial_math_veraMOD50 points·1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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u/viktor_kirchner-9 points·1 year ago

u-100 syringe, not u-40, or your math is off by factor of 6

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u/priya_weiss1 point·1 year ago

Are you using a u-100 or u-40 syringe? That changes everything.

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u/mateusz_achebeOP1 point·1 year ago

This is correct. 1mL versus 21mL is the common mistake.

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u/signe_grimaldi43 points·1 year ago·edited

u-100 syringe, not u-40, or your math is off by factor of 16

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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