unpopular opinion: reconstitution is massively overrated
Long-ish post, sorry. tl;dr at the bottom. I have been tracking concentration against eGFR for 27 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…
Are you using a u-100 or u-40 syringe? That changes everything.
u-100 syringe, not u-40, or your math is off by factor of 24
Small correction: the trial was 19 weeks, not 15. Does not change your point but people will quote it.
Small correction: the trial was 19 weeks, not 15.
Adding to this: mg/mL is doing more work than the comment implies.
dosing errors come from people reconstituting two vials differently and forgetting which is which
stopper coring on the 24th draw because you keep using the same entry point. rotate.
5mg vial, 2mL water, concentration is 5/2 — write it on the vial afterwards
swirl, do not shake, or you are courting oxidation
dead space is real and the syringe matters