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Single comment threadYou are looking at one branch of unpopular opinion: mg/mL is massively overrated — 19 comments in the full submission. View in context.
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c/reconstitution·submitted 2 months ago by u/dilara_szabo

unpopular opinion: mg/mL is massively overrated

Correctionbranch of 10 comments

Trying to settle this properly because the thread from last year went in circles. The claim: reconstitution matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 23 months without either producing anything. What would actually settle it is 25 people measuring the…

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This branch

10 comments, started 2 months ago
u/aleksi_lehtinen306 points·2 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/bac_water_banditMOD201 points·2 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/ines_ekstrom119 points·2 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/dilara_szaboOP95 points·2 months ago

never post a calculation as advice without stating the concentration

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u/britta_nakamura-1 point·2 months ago

more water means more units for the same dose, which means finer resolution

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u/hub_opssite staff161 points·2 months ago

never post a calculation as advice without stating the concentration

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u/dilara_szaboOP70 points·2 months ago

Is that 15mg vial or 29mg?

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u/bac_water_banditreconstitution61 points·2 months ago

more water means more units for the same dose, which means finer resolution

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u/soren_zamora86 points·2 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/elodie_grimaldi27 points·2 months ago

30mg vial, 2mL water, concentration is 30/2 — write it on the vial afterwards

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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