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388

what changed for me between week 15 and week 64

Question Clean Column ×9

Week 75 update. 31kg down from the start, muscle cramps basically gone since about week 32.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

631 up / 243 down72% upvoted20 commentsid 1chsu43 Jul 2026

20 comments

19 in this archive, depth 5

best — the order this archive was captured in

u/two_mil_or_one54 points·24 days ago

Strongly agree. Evidence level matters.

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u/sigrid_kaufmann33 points·24 days ago

Maintenance for 14 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/batch_number_bertievetting11 points·24 days ago·edited

purity and identity are two questions

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u/analog_alphabetMOD41 points·25 days ago

Retitled to remove editorialising. Put the evidence in the body.

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u/insulin_syringe_ianOP-9 points·25 days ago

The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/incretin_ivypharmacology34 points·25 days ago

Yeah, identity is the first question.

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u/greta_lokken16 points·24 days ago

Yeah, identity is the first question.

Disagree on that part. 98.7% and 99.3% on the same vial is normal.

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u/insulin_syringe_ianOP0 points·24 days ago

Yeah, identity is the first question.

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u/greta_lokken1 point·24 days ago·edited

research use only, handling and analysis, not administration

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u/ignacio_roos10 points·24 days ago·edited

Slight fix: the number was 98.7, not 98.6. Decimal point, but a fairly consequential one.

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u/bastian_ekstrom4 points·24 days ago

regulatory status varies by country, check yours

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u/aksel_kjaer21 points·24 days ago

Mechanistically the bit that matters is handling. It explains most of the early profile and a decent chunk of the outcome.

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[removed]15 points·24 days ago

[removed by moderator]

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u/georgi_adebayo6 points·24 days ago

Second this question. I have wondered about thymosin for 15 months and never seen a straight answer.

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u/escrow_evangelist2 points·24 days ago·edited

thymosin fragments, GH secretagogues, secretagogue, long tail

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u/prior_auth_painappeals1 point·23 days ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/honest_syringe3310 points·24 days ago

purity and identity are two questions

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The wider research-peptide catalogue: thymosin fragments, GH secretagogues, melanocortin agonists, and the long tail of three-letter analogs. Focus on identity verification, handling and the state of the evidence — not on protocols, because these are not approved for human use.

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