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c/semaglutide·posted 8 months ago by u/ahmed_okafor

[PSA] write the concentration on the vial. that is the whole post.

PSA Clean Column ×5 Cold Box ×1

Posting this because I searched for it and got nothing useful.

Setup: 1.7mg, week 56, constipation present but not ruining anything. I changed exactly one variable — weekly dosing — and tracked it for 14 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

2,819 up / 578 down83% upvoted31 commentsid fwuadq6 Nov 2025

31 comments

16 in this archive, depth 4

best — the order this archive was captured in

u/marit_coelho250 points·8 months ago

my eGFR moved before the scale did and i nearly missed it

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u/arne_restrepo102 points·8 months ago

titration speed is Wegovy plus side effects, period

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u/hassan_castellanos74 points·8 months ago

week 30 on the pen, 30kg down, this is the answer

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u/ahmed_okaforOP44 points·8 months ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/nausea_notesside effects205 points·8 months ago

my eGFR moved before the scale did and i nearly missed it

Disagree on that part. 98.6% and 98.7% on the same vial is normal.

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u/oskar_kaufmann167 points·8 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/pavel_nkemelu47 points·8 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/camila_mensa92 points·8 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/anya_erdogan40 points·8 months ago

How long were you at 12.5mg before you moved up?

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u/enzo_danquah15 points·8 months ago

How long were you at 12.5mg before you moved up?

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/kavya_radich122 points·8 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/titration_marshalMOD66 points·8 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/diego_sorensen0 points·8 months ago

week 62 on the pen, 5kg down, this is the answer

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u/titration_marshalmod · c/semaglutide1 point·8 months ago

week 56 and i am still not at maintenance, do not rush the ladder

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u/ahmed_okaforOP63 points·8 months ago

Small correction: the trial was 3 weeks, not 6. Does not change your point but people will quote it.

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u/test_it_yourselfvetting0 points·8 months ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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