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c/t2dglp1·posted 1 year ago by u/ferran_batista

[Lab] 13th independent test on QSC, and the trend is the interesting part

Caution Long Haul ×9 Sourced ×1

hypoglycaemia. That is the whole post, but I will justify it.

Everything else people worry about in c/meta is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort hypoglycaemia out first, and almost nobody does.

I say this having got it wrong for 18 months. My hs-CRP was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

1,810 up / 252 down88% upvoted38 commentsid wxtg2g22 Jun 2025

38 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/fridge_door_no264 points·1 year ago·edited

post A1c with units and assay date

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[deleted]99 points·1 year ago

[deleted]

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u/ferran_batista66 points·1 year ago

Strongly agree. A1c matters as much as weight.

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u/farid_jansen50 points·1 year ago

insulin and sulfonylurea interactions are real hypo risk

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u/cormac_danquah217 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/gentle_correctionnice about it72 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/osman_ferrari-10 points·1 year ago

Genuine question — what concentration were you at?

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u/step_count_stan274 points·1 year ago·edited

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/hamza_weiss188 points·1 year ago

Strongly agree. A1c matters as much as weight.

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u/sock_puppet_spotter115 points·1 year ago

Week 61 for me and the honest summary is: 22kg down, muscle cramps manageable, and I have thought about food maybe four times today.

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u/amylin_amyamylin146 points·1 year ago

the 62 A1c trend is the answer

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u/reship_roulette104 points·1 year ago

glycaemic control first, that is the original indication

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u/ilias_kaufmann73 points·1 year ago

I am going to push back on this slightly.

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u/gentle_correctionMOD42 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/not_my_main_nm150 points·1 year ago

no medication-stopping advice, ever

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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Independent HPLC and mass spec. The number you get is the number they found.

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c/t2dglp1 rules
  1. Insulin and sulfonylurea interactions are a real hypo risk. Do not hand-wave them.
  2. Post A1c with units and the assay date.
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