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c/t2dglp1·posted 4 months ago by u/a1c_arc

CGM vs metformin — genuinely asking which matters more

Caution

Posting this because I searched for it and got nothing useful.

Setup: 1.7mg, week 85, injection-site soreness present but not ruining anything. I changed exactly one variable — glycaemic control — and tracked it for 7 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

59 up / 2 down96% upvoted12 commentsid z6be7u27 Mar 2026

12 comments

12 in this archive, depth 5

best — the order this archive was captured in

u/lyophile_lou10 points·4 months ago

What was the batch number and which service?

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u/enzo_danquah8 points·4 months ago

hypoglycaemia risk when stacked with A1c

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u/camila_sandvik8 points·4 months ago

post A1c with units and assay date

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u/rasmus_kimani2 points·4 months ago

Strongly agree. A1c matters as much as weight.

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u/amylin_amyamylin5 points·4 months ago

What was the batch number and which service?

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u/ferran_batista7 points·4 months ago

Maintenance for 7 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/marisol_moreau2 points·4 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/farid_jansen1 point·4 months ago

the weight-loss conversation drowns out glycaemic control sometimes

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u/yannick_barros1 point·4 months ago

Did anything else change in the same window?

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u/a1c_arcOPT2D1 point·4 months ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/protein_first_pnutrition0 points·4 months ago

Respectfully this is a sample of one presented as a finding.

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u/cloudy_vial_carol2 points·4 months ago

the A1c change is the signal

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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