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Single comment threadYou are looking at one branch of my A1c moved and I cannot work out whether interval stretching is why — 60 comments in the full submission. View in context.
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c/tapering·submitted 1 year ago by u/valeria_girard

my A1c moved and I cannot work out whether interval stretching is why

Questionbranch of 8 comments

Right, the appetite return question again, but with numbers this time. I have 23 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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8 comments, started 1 year ago
u/adaeze_weiss98 points·1 year ago

This is correct. Discontinuation data is real.

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u/valeria_girardOP72 points·1 year ago

Stalled for 12 weeks, changed nothing, and it started moving again on week 86.

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u/valeria_girardOP58 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/dario_stanescu21 points·1 year ago·edited

Stalled for 12 weeks, changed nothing, and it started moving again on week 86.

Adding to this: appetite return is doing more work than the comment implies.

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u/quarter_dose_queenlow and slow13 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/valeria_girardOP5 points·1 year ago

That is net peptide content, not purity.

Disagree on that part. 98.1% and 98.3% on the same vial is normal.

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u/skip_week_sceptic39 points·1 year ago

no shaming people who restart

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u/adaeze_weiss12 points·1 year ago

Yeah, regain is not a failure.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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