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Single comment threadYou are looking at one branch of tried interval stretching for 2 weeks. here is what happened. — 28 comments in the full submission. View in context.
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c/tapering·submitted 9 months ago by u/janek_ferrari

tried interval stretching for 2 weeks. here is what happened.

Trial Databranch of 5 comments

Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 13 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have reflux I did…

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This branch

5 comments, started 9 months ago
u/border_paperwork96 points·9 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/skip_week_sceptic34 points·9 months ago

Small correction: the trial was 22 weeks, not 36. Does not change your point but people will quote it.

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u/border_paperwork16 points·9 months ago

the people who came off and restarted without shame

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u/zeynep_weiss13 points·9 months ago

the 22 week discontinuation arm is the data

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u/ilias_nakamura3 points·9 months ago

the 22 week discontinuation arm is the data

Disagree on that part. 99.0% and 98.9% on the same vial is normal.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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