GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of why does nobody talk about regain — 38 comments in the full submission. View in context.
1k
c/tapering·submitted 6 months ago by u/preservative_free_p

why does nobody talk about regain

Questionbranch of 8 comments

appetite return. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort appetite return out first, and almost nobody does. I say this having got it wrong for 7 months. My ApoB…

Read the full submission and all 38 comments →

This branch

8 comments, started 6 months ago
u/helga_vermeulen35 points·6 months ago

appetite return timelines vary appetite return

replysharereportpermalink
u/preservative_free_pOP20 points·6 months ago

Maintenance for 7 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

replysharereportpermalink
u/ismael_eriksen16 points·6 months ago·edited

Disagree but this is the good kind of wrong — it is specific enough to be checked.

replysharereportpermalink
u/source_or_silence16 points·6 months ago·edited

appetite return timelines vary appetite return

replysharereportpermalink
u/preservative_free_pOP8 points·6 months ago

Small correction: the trial was 8 weeks, not 34. Does not change your point but people will quote it.

replysharereportpermalink
[removed]11 points·6 months ago

[removed by moderator]

replysharereportpermalink
load more comments (1) →
u/nora_ramos14 points·6 months ago

STEP 1 and SURMOUNT-4 discontinuation arms show regain

replysharereportpermalink

← back to the whole thread

About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

20kmembers
62submissions
Jun 2024created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/tapering
c/tapering rules
  1. Cite the discontinuation data rather than guessing at regain rates.
  2. No shaming people who restart.
  3. Say how long you were on and at what dose before you tapered.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/taper_off_tabithau/maintenance_mode_maxu/skip_week_sceptic
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →