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c/tirzepatide·submitted 6 months ago by u/gentle_correction

[Vendor] QST order #10 — Spain, 27 days, no drama, receipts inside

Trial Databranch of 10 comments

Posting this because I searched for it and got nothing useful. Setup: 5mg, week 10, constipation present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 24 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am…

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10 comments, started 6 months ago
u/titration_marshalmod · c/semaglutide475 points·6 months ago

How long at each step before you escalated?

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u/swirl_dont_shakereconstitution187 points·6 months ago

week 43 on Mounjaro and the appetite profile is genuinely different from sema

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u/laila_yilmaz-14 points·6 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/sten_palacios1 point·6 months ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/kaia_wojcik1 point·6 months ago·edited

Did you stay on semaglutide or switch? The outcome is different if you are comparing.

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u/marit_sandvik1 point·6 months ago·edited

the appetite change on tirz is more than just reduced hunger, it is different machinery

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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