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c/tirzepatide·submitted 1 year ago by u/emil_wojcik

unpopular opinion: 15mg is massively overrated

Titrationbranch of 8 comments

Posting this because I searched for it and got nothing useful. Setup: 2.5mg, week 52, constipation present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I…

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8 comments, started 1 year ago
u/quiet_moderatorMOD237 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/sanne_novak330 points·1 year ago

week 96 on Mounjaro and the appetite profile is genuinely different from sema

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u/emil_wojcik274 points·1 year ago

dual agonism is Mounjaro, do not generalise from semaglutide

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u/ahmed_iyer264 points·1 year ago·edited

the the food-noise thing from tirz is different, not necessarily worse

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u/coring_the_stopper200 points·1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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