GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of [Discussion] can we stop arguing about Zepbound until somebody posts a number — 47 comments in the full submission. View in context.
2.8k
c/tirzepatide·submitted 1 year ago by u/incretin_ivy

[Discussion] can we stop arguing about Zepbound until somebody posts a number

Discussionbranch of 9 comments

Genuinely asking, not being difficult. Everyone in c/semaglutide repeats that dual agonist is important. I believe it, but I have never seen anyone show why, and when I search I get 6 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

Read the full submission and all 47 comments →

This branch

9 comments, started 1 year ago
u/throwaway_titration471 points·1 year ago

do not crack the pen, we have been over this

replysharereportpermalink
u/curious_panel_only125 points·1 year ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

replysharereportpermalink
u/cato_girard160 points·1 year ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

replysharereportpermalink
u/yusuf_ramos0 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

replysharereportpermalink
u/titration_marshalmod · c/semaglutide0 points·1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

replysharereportpermalink
u/kian_ekstrom1 point·1 year ago

week 73 on Mounjaro and the appetite profile is genuinely different from sema

replysharereportpermalink
u/incretin_ivypharmacology1 point·1 year ago

the 15mg is the top of the pen, not the required dose

replysharereportpermalink
u/noor_hovland1 point·1 year ago·edited

Zepbound and Mounjaro are literally the same drug, the name is the only difference

replysharereportpermalink
u/incretin_ivyOPpharmacology1 point·1 year ago·edited

How long at each step before you escalated?

replysharereportpermalink

← back to the whole thread

About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.com
Sponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.