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c/trialwatch·submitted 1 months ago by u/careful_gradient_again

why does nobody talk about hazard ratio

Trial Databranch of 7 comments

Week 96 update. 22kg down from the start, muscle cramps basically gone since about week 41. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps. The part that surprised me is how much of this is admin.…

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7 comments, started 1 months ago
u/yusuf_ramos81 points·1 months ago

Half-life is about 168 hours, so steady state lands around week 23–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/careful_gradient_againOP35 points·1 months ago

dropout handling matters, especially on GI-heavy populations

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u/receipts_or_nothingvetting18 points·1 months ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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u/line_demir23 points·1 months ago

Not convinced. The evidence does not support that reading.

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u/ewan_tulloch19 points·1 months ago

press release STEP posts must be flaired until a publication exists

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u/tomas_kimani6 points·1 months ago

dropout handling matters, especially on GI-heavy populations

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u/receipts_or_nothingvetting29 points·1 months ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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