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c/trialwatch·submitted 3 months ago by u/nhs_waitlist_n

what would you tell week-1 you about SELECT

Statsbranch of 7 comments

Confession thread, sort of. I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have reflux I…

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7 comments, started 3 months ago
u/trialwatch_theoMOD16 points·3 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/nhs_waitlist_nOPUK-34 points·3 months ago

the relative risk reduction in headlines is not the whole story

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u/anders_karlsen1 point·3 months ago

dropout handling matters, especially on GI-heavy populations

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u/plateau_patrol1 point·3 months ago

dropout handling matters, especially on GI-heavy populations

Yes, exactly this, and it is the bit that took me 52 weeks to accept.

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u/nhs_waitlist_nOPUK1 point·3 months ago

STEP 1 readout: 97.9% mean weight loss, absolute numbers matter. Spread around that mean is enormous.

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[deleted]8 points·3 months ago

[deleted]

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u/rina_sobczak4 points·3 months ago

give the trial name, phase, n, and primary endpoint in the body

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