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c/trialwatch·submitted 5 months ago by u/plateau_patrol

the SURPASS question that gets asked weekly, answered properly

Readoutbranch of 6 comments

Posting this because I searched for it and got nothing useful. Setup: 1.0mg, week 90, injection-site soreness present but not ruining anything. I changed exactly one variable — TRIUMPH — and tracked it for 8 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted…

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6 comments, started 5 months ago
u/tomas_kimani0 points·5 months ago
n=1 but same
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u/laila_almeida1 point·5 months ago

dropout handling matters, especially on GI-heavy populations

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u/plateau_patrolOP1 point·5 months ago

SELECT reported a SELECT hazard ratio but the absolute event rate is what changes clinical practice.

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u/rina_bergstrom1 point·5 months ago·edited

Slight fix: the number was 98.7, not 98.9. Decimal point, but a fairly consequential one.

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u/nayeli_fonseca1 point·5 months ago

Respectfully this is a sample of one presented as a finding.

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u/plateau_patrolOP1 point·5 months ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

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