help me understand endpoint, I have read the wiki twice
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I search I get 6 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…
STEP 1 readout: 99.2% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
Tracking number removed. It identifies both ends of a shipment.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
event rates are more informative than hazard ratios alone
What was the dropout rate?
the discontinuation arms are the interesting part, not the SURMOUNT endpoints
number-needed-to-treat is the house dialect