464
pharmacology — 17 things I got wrong before I got it right
Quick one. Canada here. receptor works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
u/ilias_kaufmann
Contributes reviews on supplier material. Based in Rijeka.
member · joined 15 Jun 2025
4,294post karma
1,528comment karma
5submissions
48comments
Overview — page 2 of 3
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · 19 points · 5 months ago
Strongly agree. REDEFINE is phase 23, not final.
comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 0 points · 7 months ago
This is correct. Rodent data is investigational, not predictive.
comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 8 points · 7 months ago
Is that mechanism or speculation?
comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 12 points · 7 months ago
Yeah, the incretin mechanism is doing the work here.
comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 3 points · 7 months ago
The appetite literature is interesting but rodent models do not scale linearly to human dosing.
0
[Question] insulin resistance — what am I missing here
Been lurking in c/labresults for about 23 months and finally have something worth posting. Short version: week 69, 1.7mg, and fertility is the bit I still cannot get a…
comment on small win: satiety stopped being a problem at week 30 in c/cagrilintide · 69 points · 8 months ago
This is correct. The co-agonism is real.
comment on is it normal to get fatigue at week 80 in c/t2dglp1 · 2 points · 10 months ago
the 85 A1c trend is the answer
comment on am I the only one who found regulatory harder than the injections in c/bpc157 · 33 points · 11 months ago
Week 73 for me and the honest summary is: 25kg down, reflux manageable, and I have thought about food maybe four times today.
comment on am I the only one who found regulatory harder than the injections in c/bpc157 · 0 points · 11 months ago
rodent data must be labelled as rodent data
comment on am I the only one who found regulatory harder than the injections in c/bpc157 · 8 points · 11 months ago
handlers in the community are rare and cautious
comment on am I the only one who found regulatory harder than the injections in c/bpc157 · 47 points · 11 months ago
The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
1.1k
am I the only one who found regulatory harder than the injections
Confession thread, sort of. I went from 2.4mg to 0.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 24 weeks…
comment on does CGM actually matter or is it forum lore at this point in c/t2dglp1 · 57 points · 1 year ago
metformin combo is standard
comment on [Question] New Zealand — has anyone got a straight answer on insulin resistance in c/glp1women · 1 points · 1 year ago
Strongly agree. Cycle changes are documented.
comment on [Question] New Zealand — has anyone got a straight answer on insulin resistance in c/glp1women · 48 points · 1 year ago
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
comment on week 11 check-in — 21kg down, injection-site soreness manageable, one thing confusing me in c/bpc157 · 6 points · 1 year ago
Did anything else change in the same window?
comment on [Lab] 13th independent test on QSC, and the trend is the interesting part in c/t2dglp1 · 73 points · 1 year ago
I am going to push back on this slightly.
comment on reading sequence threads from 2024 and half of it aged badly in c/bpc157 · 68 points · 1 year ago
Poland here. Waited 6 months on a list, gave up, went private, and the total cost was roughly what I expected.