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[Question] amylin — what am I missing here
Long-ish post, sorry. tl;dr at the bottom. I have been tracking cagrilintide against eGFR for 7 weeks because I could not find anyone who had. The correlation is weaker…
u/ilias_kaufmann
Contributes reviews on supplier material. Based in Rijeka.
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Overview — page 3 of 3
comment on [Question] mechanism — what am I missing here in c/glp1science · -54 points · 1 year ago
The confident tone is doing a lot of work that the evidence is not.
comment on my ferritin moved and I cannot work out whether T2D is why in c/t2dglp1 · 1 points · 1 year ago
I am going to push back on this slightly.
comment on genuine question about amylin that I am slightly embarrassed to ask in c/cagrilintide · 14 points · 1 year ago
Yeah, amylin is doing different work than GLP-1.
Adding to this: co-agonism is doing more work than the comment implies.
comment on A1c: the version I wish someone had shown me in week 1 in c/t2dglp1 · 0 points · 1 year ago
Second this question. I have wondered about CGM for 20 months and never seen a straight answer.
comment on [Lab] 2th independent test on QSC, and the trend is the interesting part in c/t2dglp1 · 1 points · 1 year ago
glycaemic control first, that is the original indication
comment on 7 months in and fertility is still the thing I get wrong in c/glp1women · 29 points · 1 year ago
Not to be pedantic but PCOS and insulin resistance are being used interchangeably and they are not interchangeable in real life.
comment on [Discussion] the receptor advice in here is 4 years out of date in c/glp1science · 71 points · 1 year ago
rodent half-life tells you what to investigate, not what to expect in humans
comment on insulin resistance — 21 things I got wrong before I got it right in c/glp1women · 10 points · 1 year ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on anyone else notice discontinuation kicking in around week 29 in c/tapering · 98 points · 1 year ago
the 16 week discontinuation arm is the data
comment on [Question] amylin — what am I missing here in c/cagrilintide · 19 points · 2 years ago
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does satiety.
comment on [Question] amylin — what am I missing here in c/cagrilintide · 6 points · 2 years ago
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does satiety.
comment on Germany: mechanism, and what it actually costs here in c/glp1science · 89 points · 2 years ago
the half-life is incretin, affects steady state timing