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u/iman_castellanos

Contributes reviews on supplier material. Based in Salvador.

member · joined 17 Aug 2025

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Comments — page 4 of 5

comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · -6 points · 6 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 42 points · 6 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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comment on small win: TRIUMPH stopped being a problem at week 5 in c/retatrutide · 150 points · 6 months ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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comment on small win: TRIUMPH stopped being a problem at week 5 in c/retatrutide · 282 points · 6 months ago

Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.

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comment on [Meta] proposal — a flair for co-agonism posts in c/cagrilintide · 55 points · 6 months ago

Yeah, amylin is doing different work than GLP-1.

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comment on [Discussion] can we stop arguing about glucagon until somebody posts a number in c/retatrutide · 165 points · 6 months ago

the glucagon component changes the side effect profile, not just the efficacy

Yes, exactly this, and it is the bit that took me 5 weeks to accept.

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comment on the identity question that gets asked weekly, answered properly in c/researchpeptides · 1 points · 6 months ago

You have restated the marketing copy. What is the actual substance here.

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comment on what changed for me between week 50 and week 4 in c/sideeffects · 86 points · 6 months ago

IANAD and neither is anyone upvoting this

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comment on [Discussion] can we stop arguing about nausea until somebody posts a number in c/sideeffects · 0 points · 7 months ago

week 41 and the the food-noise thing is finally getting better

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comment on tried gallbladder for 5 weeks. here is what happened. in c/sideeffects · 40 points · 7 months ago

Not convinced. The evidence does not support that reading.

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comment on am I the only one who found TB-500 harder than the injections in c/researchpeptides · 42 points · 8 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on [Results] 42 weeks, 46kg, and reflux was the hard part in c/sideeffects · 13 points · 8 months ago

severe abdominal pain is an urgent-care question, not a forum question

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comment on small win: packaging stopped being a problem at week 66 in c/coldchain · 61 points · 9 months ago

data logger is the standard, gut feeling is not

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comment on 21 months in and sulphur burps is still the thing I get wrong in c/sideeffects · 59 points · 9 months ago

sulphur burps are disgusting but not dangerous, 20 weeks and they stopped

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comment on 21 months in and sulphur burps is still the thing I get wrong in c/sideeffects · 1 points · 9 months ago

nausea on day 2 is normal, nausea after week 74 is worth checking

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comment on 21 months in and sulphur burps is still the thing I get wrong in c/sideeffects · 44 points · 9 months ago

nausea on day 2 is normal, nausea after week 79 is worth checking

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comment on reading Wegovy threads from 2024 and half of it aged badly in c/semaglutide · 1 points · 9 months ago

stalled at 12.5mg, went up, and regretted it, the stall would have broken anyway

Yes, exactly this, and it is the bit that took me 72 weeks to accept.

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comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 1 points · 10 months ago

triple agonism is phase 2, do not generalise

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comment on [Meta] proposal — a flair for SURPASS posts in c/trialwatch · 26 points · 10 months ago

Is that absolute or relative risk reduction?

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comment on [Discussion] the cagrilintide advice in here is 21 years out of date in c/cagrilintide · 65 points · 10 months ago

long-acting amylin is CagriSema, different satiety profile

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