u/iman_castellanos

stability after excursion is not zero, it is dose-dependent

Sceptical. If this were true we would see it reflected in the data and we do not.

the the food-noise thing passes. i promise. not medical advice.

the food-noise thing stops around week 18 for most people

The constipation passes. I kept a log and the timeline was the only useful thing. 18 weeks and it was basically gone.

hypoglycaemia risk when stacked with A1c

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

Reconstituted or dry powder?

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

My version: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part. Nobody believes that until they do it.

What are you comparing it against though?

This is correct.

Yes, exactly this, and it is the bit that took me 78 weeks to accept.

What colour is the pen? Wegovy and Ozempic use different formulations.

Not convinced. The evidence does not support that reading.

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

REDEFINE phase 23 readouts are interesting but 23 person REDEFINE is different from 23 trial REDEFINE.

Not to be pedantic but data logger and lyophilised are being used interchangeably and they are not interchangeable in real life.

phase 2 numbers are not maintenance numbers, cite the trial

Which country? Half the answers in this thread only apply in Germany.

the relative risk reduction in headlines is not the whole story