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IM

u/iman_castellanos

Contributes reviews on supplier material. Based in Salvador.

member · joined 17 Aug 2025

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Overview — page 5 of 5

comment on reading Wegovy threads from 2024 and half of it aged badly in c/semaglutide · 1 points · 9 months ago

stalled at 12.5mg, went up, and regretted it, the stall would have broken anyway

Yes, exactly this, and it is the bit that took me 72 weeks to accept.

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comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 1 points · 10 months ago

triple agonism is phase 2, do not generalise

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comment on [Meta] proposal — a flair for SURPASS posts in c/trialwatch · 26 points · 10 months ago

Is that absolute or relative risk reduction?

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comment on [Discussion] the cagrilintide advice in here is 21 years out of date in c/cagrilintide · 65 points · 10 months ago

long-acting amylin is CagriSema, different satiety profile

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comment on my hs-CRP moved and I cannot work out whether gallbladder is why in c/sideeffects · 1 points · 10 months ago

The fatigue was genuinely awful for three weeks and then simply stopped.

Disagree on that part. 97.4% and 98.7% on the same vial is normal.

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comment on [Discussion] the plateau advice in here is 15 years out of date in c/semaglutide · 24 points · 11 months ago

Yeah, 78 weeks on 5mg, same pattern, same timing.

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comment on week 11 check-in — 31kg down, muscle cramps manageable, one thing confusing me in c/retatrutide · 197 points · 11 months ago

heart rate and dose escalation need actual measurements, not impressions

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comment on stalled for 9 weeks at 5mg and I refuse to panic this time in c/semaglutide · 51 points · 11 months ago

the quiet is real. the food noise just stops.

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comment on co-agonism — my 6-week log, condensed into one table in c/cagrilintide · 0 points · 11 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on help me understand endpoint, I have read the wiki twice in c/trialwatch · 109 points · 12 months ago

Crossposting this to c/bloodwork because the people who need it are not reading this community.

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comment on does CGM actually matter or is it forum lore at this point in c/t2dglp1 · 35 points · 1 year ago

Ireland here. Waited 18 months on a list, gave up, went private, and the total cost was roughly what I expected.

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comment on does CGM actually matter or is it forum lore at this point in c/t2dglp1 · 157 points · 1 year ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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comment on does CGM actually matter or is it forum lore at this point in c/t2dglp1 · 20 points · 1 year ago

insulin and sulfonylurea interactions are real hypo risk

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comment on [Results] 42 weeks, 30kg, and hair loss was the hard part in c/sideeffects · 57 points · 1 year ago

Not convinced. The evidence does not support that reading.

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comment on genuine question about titration that I am slightly embarrassed to ask in c/semaglutide · 1 points · 1 year ago

That is net peptide content, not purity. Different number, different meaning.

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comment on someone explain seizure to me like I have not read a paper in years in c/customs · 3 points · 1 year ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

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comment on switched from 1.0mg to 2.5mg and the sulphur burps got better, not worse in c/sideeffects · 0 points · 1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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comment on does seizure actually matter or is it forum lore at this point in c/customs · 15 points · 1 year ago

the 11mg import allowance is Denmark-specific

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comment on satiety — 14 things I got wrong before I got it right in c/cagrilintide · 0 points · 1 year ago

This is correct. The co-agonism is real.

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