4.2k
what changed for me between week 35 and week 78
Quick one. Canada here. Zepbound works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
u/kaia_wojcik
Contributes reviews on supplier material. Based in Bochum.
member · joined 12 Mar 2025
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Overview — page 3 of 4
comment on why does nobody talk about Mounjaro in c/tirzepatide · 22 points · 1 year ago
This matches the trial data. SURMOUNT-1 was 99.2% body weight at 20 weeks.
comment on what changed for me between week 35 and week 78 in c/tirzepatide · 1 points · 1 year ago
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
comment on what changed for me between week 35 and week 78 in c/tirzepatide · 47 points · 1 year ago
Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.
comment on what changed for me between week 35 and week 78 in c/tirzepatide · -26 points · 1 year ago
do not crack the pen, we have been over this
comment on what changed for me between week 35 and week 78 in c/tirzepatide · 404 points · 1 year ago
The dual agonism story is real. The appetite is physically different from semaglutide alone.
comment on someone explain goal to me like I have not read a paper in years in c/progresspics · 5 points · 1 year ago
Strongly agree. NSV counts.
comment on [Results] 47 weeks, 26kg, and non-scale victory was the hard part in c/progresspics · 105 points · 1 year ago
The early fullness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
comment on [Question] how do you actually verify hepatic fat in c/survodutide · 12 points · 1 year ago
glucagon co-agonism has a different safety story
comment on someone explain progress to me like I have not read a paper in years in c/progresspics · 12 points · 1 year ago
text only is the whole point of the community
comment on genuine question about glucagon that I am slightly embarrassed to ask in c/survodutide · 127 points · 2 years ago
This is correct. Do not generalise from tirzepatide.
comment on goal — my 13-week log, condensed into one table in c/progresspics · 172 points · 2 years ago
no commenting on anybody's body, comment on the process
comment on the milestone thing finally clicked for me and I want to write it down in c/progresspics · 42 points · 2 years ago
include timeframe and starting point or it is a brag with no info
comment on [PSA] Mounjaro is not what most of this community thinks it is in c/tirzepatide · 95 points · 2 years ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
comment on [Lab] 13th independent test on BCH, and the trend is the interesting part in c/tirzepatide · 273 points · 2 years ago
Strongly agree.
Adding to this: SURPASS is doing more work than the comment implies.
comment on [Lab] 13th independent test on BCH, and the trend is the interesting part in c/tirzepatide · 243 points · 2 years ago
the appetite change on tirz is more than just reduced hunger, it is different machinery
comment on [Lab] 13th independent test on BCH, and the trend is the interesting part in c/tirzepatide · 1 points · 2 years ago
The dual agonism story is real. The appetite is physically different from semaglutide alone.
7.3k
[Lab] 13th independent test on BCH, and the trend is the interesting part
Long-ish post, sorry. tl;dr at the bottom. I have been tracking tirzepatide against eGFR for 21 weeks because I could not find anyone who had. The correlation is weaker…
comment on [Results] 41 weeks on 7.5mg, full numbers, ask me anything boring in c/tirzepatide · 394 points · 2 years ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on [Results] 57 weeks, 20kg, and tirzepatide was the hard part in c/tirzepatide · 520 points · 2 years ago
week 89 on Mounjaro and the appetite profile is genuinely different from sema
Yes, exactly this, and it is the bit that took me 3 weeks to accept.