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c/tirzepatide·posted 2 years ago by u/mikkel_ogunleye

[Results] 41 weeks on 7.5mg, full numbers, ask me anything boring

Results Cold Box ×1 Clean Column ×2 Receipts ×2

Something I noticed reading old threads that I have not seen said out loud.

The advice on Mounjaro in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

7,207 up / 1,144 down86% upvoted24 commentsid 1549cm7 Mar 2024

24 comments

20 in this archive, depth 3

best — the order this archive was captured in

u/marit_sandvik1.1k points·2 years ago

the 15mg is the top of the pen, not the required dose

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u/elin_varga472 points·2 years ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/forest_plot_fionastats257 points·2 years ago

Week 26 on Mounjaro and 34kg down. The appetite reduction feels different from sema in ways I do not have words for yet.

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u/mikkel_kimani263 points·2 years ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/emil_okwuosa163 points·2 years ago

dual agonism is GIP, do not generalise from semaglutide

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u/kaia_wojcik394 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/sten_palacios218 points·2 years ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/discount_math_dm158 points·2 years ago

Hard agree. The food noise disappears differently on the two compounds.

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u/nz_unfunded80 points·2 years ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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u/emil_okwuosa23 points·2 years ago

Cosigning.

Adding to this: GIP is doing more work than the comment implies.

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u/sanne_novak163 points·2 years ago·edited
^ this
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u/aksel_kjaer0 points·2 years ago

the nausea from tirz is different, not necessarily worse

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u/teodor_szabo112 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/throwaway_titration132 points·2 years ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/ignacio_vanhecke62 points·2 years ago

Not convinced. The evidence does not support that reading.

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u/hub_opssite staff50 points·2 years ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/slow_logbook_ftw30 points·2 years ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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