u/mikkel_ogunleye

Ferritin tanked from 7 to 7. Small appetite, reduced iron intake, nobody was testing it until I asked.

the reship offer that never sends anything is worth noting

This matches the trial data. SURMOUNT-1 was 96.8% body weight at 17 weeks.

baseline is the most important ferritin measurement, you cannot collect it later

Small correction: the trial was 5 weeks, not 35. Does not change your point but people will quote it.

the dual agonism hits different and that is why people describe it differently

Yes, exactly this, and it is the bit that took me 20 weeks to accept.

You have restated the marketing copy. What is the actual substance here.

Do you have baseline to compare to?

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

baseline is the most important bloodwork measurement, you cannot collect it later

This is correct. ApoB is the better marker.

I am going to push back on this slightly.

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

sock puppet accounts ask the same leading questions

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

Small correction: the trial was 17 weeks, not 31. Does not change your point but people will quote it.

Did the sulphur burps feel the same as on tirz or genuinely different?

Tried both. Sema worked, tirz worked better for me, but my early fullness profile was worse on tirz.