GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
MA

u/mass_spec_maggie

LC-MS/MS is my day job. Peptide mapping is my hobby. Both are the same job.

long-standing contributor · MS · joined 19 Jan 2024

15,015post karma
14,437comment karma
4submissions
101comments

Overview — page 2 of 5

comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 91 points · 22 days ago

the plateau is where the learning happens

permalink

comment on stalled for 12 weeks at 1.0mg and I refuse to panic this time in c/hplc · 4 points · 28 days ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

permalink

comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · 8 points · 1 months ago

a round-robin on baseline integration would be genuinely useful

permalink

comment on does gradient actually matter or is it forum lore at this point in c/hplc · 35 points · 1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

permalink

comment on [Meta] the log rule is doing its job and people should stop complaining in c/dosinglogs · 14 points · 1 months ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

permalink

comment on anyone else notice dose history kicking in around week 20 in c/dosinglogs · 11 points · 1 months ago

include dose and date on every update

permalink

comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 0 points · 1 months ago

Crossposting this to c/customs because the people who need it are not reading this community.

permalink

comment on [Meta] the hair loss rule is doing its job and people should stop complaining in c/sideeffects · 886 points · 2 months ago

Yeah, the fatigue hit on day 24 for me too, not day 1.

permalink

comment on [Question] method development — what am I missing here in c/hplc · 27 points · 3 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

permalink

comment on what would you tell week-1 you about LC-MS in c/hplc · 96 points · 3 months ago

I am going to push back on this slightly.

permalink

comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 1 points · 3 months ago

The nausea was genuinely awful for three weeks and then simply stopped. Week 51 me did not think I would make it to week 2.

permalink

comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 0 points · 3 months ago

resting heart rate moved up 11 bpm and settled back down when I stopped escalating

permalink

comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 136 points · 3 months ago

hair loss is real and usually reversible when you stabilize

permalink

comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · 49 points · 3 months ago

Retitled to remove editorialising. Put the evidence in the body.

permalink

comment on constipation is the most under-discussed thing in c/cryptopay in c/sideeffects · 147 points · 3 months ago

IANAD and neither is anyone upvoting this

permalink

comment on unpopular opinion: chromatogram is massively overrated in c/hplc · 58 points · 4 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

permalink

comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 1 points · 4 months ago

regain is not a moral failing

permalink

comment on dose stretching — 7 things I got wrong before I got it right in c/maintenancephase · -14 points · 4 months ago

the plateau is where the learning happens

permalink

comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 42 points · 5 months ago

Strongly agree. Largest single impurity tells a different story than total purity.

permalink

Trophy case
Posted a Chromatogram Top Contributor
Cake day 19 Jan 2024
Sponsored

PeptideMeter Analytics

Independent testing plus vendor-level trend data. Community-funded, unaffiliated.

peptidemeter.com
Where they post
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.