Right, the constipation question again, but with numbers this time. I have 13 data points over 36 weeks. The pattern is consistent enough that I do not think it is…
u/mass_spec_maggie
LC-MS/MS is my day job. Peptide mapping is my hobby. Both are the same job.
long-standing contributor · MS · joined 19 Jan 2024
Overview — page 2 of 5
comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 91 points · 22 days ago
the plateau is where the learning happens
comment on stalled for 12 weeks at 1.0mg and I refuse to panic this time in c/hplc · 4 points · 28 days ago
Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.
comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · 8 points · 1 months ago
a round-robin on baseline integration would be genuinely useful
comment on does gradient actually matter or is it forum lore at this point in c/hplc · 35 points · 1 months ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on [Meta] the log rule is doing its job and people should stop complaining in c/dosinglogs · 14 points · 1 months ago
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
comment on anyone else notice dose history kicking in around week 20 in c/dosinglogs · 11 points · 1 months ago
include dose and date on every update
comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 0 points · 1 months ago
Crossposting this to c/customs because the people who need it are not reading this community.
comment on [Meta] the hair loss rule is doing its job and people should stop complaining in c/sideeffects · 886 points · 2 months ago
Yeah, the fatigue hit on day 24 for me too, not day 1.
comment on [Question] method development — what am I missing here in c/hplc · 27 points · 3 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on what would you tell week-1 you about LC-MS in c/hplc · 96 points · 3 months ago
I am going to push back on this slightly.
comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 1 points · 3 months ago
The nausea was genuinely awful for three weeks and then simply stopped. Week 51 me did not think I would make it to week 2.
comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 0 points · 3 months ago
resting heart rate moved up 11 bpm and settled back down when I stopped escalating
comment on does gallbladder actually matter or is it forum lore at this point in c/sideeffects · 136 points · 3 months ago
hair loss is real and usually reversible when you stabilize
comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · 49 points · 3 months ago
Retitled to remove editorialising. Put the evidence in the body.
comment on constipation is the most under-discussed thing in c/cryptopay in c/sideeffects · 147 points · 3 months ago
IANAD and neither is anyone upvoting this
comment on unpopular opinion: chromatogram is massively overrated in c/hplc · 58 points · 4 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 1 points · 4 months ago
regain is not a moral failing
comment on dose stretching — 7 things I got wrong before I got it right in c/maintenancephase · -14 points · 4 months ago
the plateau is where the learning happens
comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 42 points · 5 months ago
Strongly agree. Largest single impurity tells a different story than total purity.