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u/nhs_waitlist_n

UK. Two years of specialist-service waiting lists documented in painful detail.

long-standing contributor · UK · joined 19 Dec 2023

5,713post karma
8,222comment karma
5submissions
98comments

Comments — page 3 of 5

comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 240 points · 6 months ago

i wish i had read this 10 months ago

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comment on receptor — 8 things I got wrong before I got it right in c/glp1science · 27 points · 6 months ago

Half-life is about 168 hours, so steady state lands around week 15–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on 21 months in and pharmacology is still the thing I get wrong in c/glp1science · 15 points · 6 months ago

receptor distribution matters, GLP-1 is not everywhere

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comment on switched from 1.0mg to 0.5mg and the injection-site soreness got better, not worse in c/maintenancephase · 286 points · 7 months ago

weight moves within 12kg and that is normal

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comment on private prescription vs MHRA — genuinely asking which matters more in c/glp1uk · 43 points · 7 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on help me understand UK, I have read the wiki twice in c/glp1uk · 166 points · 7 months ago

no naming online pharmacies that prescribe without a consultation

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comment on help me understand UK, I have read the wiki twice in c/glp1uk · 499 points · 7 months ago

Boots stock check: called 17 locations in Germany, 31 had 15mg in stock. Regional variation is real.

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comment on is it normal to get muscle cramps at week 39 in c/glp1uk · 17 points · 8 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on anyone else notice private prescription kicking in around week 4 in c/glp1uk · 12 points · 8 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on 20 months in and half-life is still the thing I get wrong in c/glp1science · 198 points · 9 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on genuine question about A1c that I am slightly embarrassed to ask in c/t2dglp1 · 27 points · 9 months ago

Second this question. I have wondered about T2D for 22 months and never seen a straight answer.

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comment on [Vendor] QST order #9 — Spain, 35 days, no drama, receipts inside in c/glp1uk · 2 points · 10 months ago

Strongly agree. MHRA is region-specific.

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comment on [Discussion] we are measuring UK at the wrong time and calling it noise in c/glp1uk · 163 points · 10 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on [Lab] 23th independent test on QSC, and the trend is the interesting part in c/glp1uk · 67 points · 11 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on reading confirmations threads from 2024 and half of it aged badly in c/cryptopay · -18 points · 11 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on [Vendor] QST order #20 — Denmark, 27 days, no drama, receipts inside in c/maintenancephase · 2 points · 11 months ago

weight moves within 21kg and that is normal

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comment on does MHRA actually matter or is it forum lore at this point in c/glp1uk · 0 points · 1 year ago

Small correction: the trial was 7 weeks, not 35. Does not change your point but people will quote it.

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comment on does mechanism actually matter or is it forum lore at this point in c/glp1science · 30 points · 1 year ago

the 22-day half-life means week 22 is still ramp-up pharmacokinetically

Adding to this: receptor is doing more work than the comment implies.

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comment on am I the only one who found glycaemic control harder than the injections in c/t2dglp1 · 0 points · 1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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comment on SURMOUNT: what the trials say vs what this community says in c/trialwatch · 4 points · 1 year ago

This is correct. Discontinuation arms show the regain reality.

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