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u/nils_tulloch

Contributes reviews on supplier material. Based in Vaasa.

member · joined 13 Apr 2025

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Comments — page 2 of 3

comment on the regain question that gets asked weekly, answered properly in c/maintenancephase · 40 points · 9 months ago

This is correct. Weight variance is normal at maintenance.

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comment on three years of goal weight threads, summarised so you do not have to read them in c/maintenancephase · 133 points · 9 months ago

Small correction: the trial was 8 weeks, not 34. Does not change your point but people will quote it.

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comment on small win: hazard ratio stopped being a problem at week 51 in c/trialwatch · 244 points · 9 months ago

the VendorInvestigate number or it did not happen

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comment on does regain actually matter or is it forum lore at this point in c/maintenancephase · 9 points · 10 months ago

regain after taper is expected, plan for it

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comment on week 91 check-in — 37kg down, early fullness manageable, one thing confusing me in c/trialwatch · 1 points · 10 months ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 6 points · 11 months ago

the lowest dose you can stay on is not the lowest dose that works

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comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 17 points · 11 months ago

Yeah, maintenance is the boring part and the important part.

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comment on anyone else notice regain kicking in around week 90 in c/maintenancephase · 3 points · 12 months ago

the plateau is where the learning happens

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comment on [Discussion] the DHL advice in here is 12 years out of date in c/intlshipping · 8 points · 1 year ago

Yeah, the lane data is more useful than single reports.

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comment on stalled for 3 weeks at 15mg and I refuse to panic this time in c/intlshipping · 3 points · 1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on [Meta] proposal — a flair for shipping posts in c/intlshipping · 95 points · 1 year ago

Half-life is about 168 hours, so steady state lands around week 21–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on am I the only one who found goal weight harder than the injections in c/maintenancephase · 59 points · 1 year ago

the plateau is where the learning happens

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comment on [PSA] lowest effective dose is not what most of this community thinks it is in c/maintenancephase · 12 points · 1 year ago

weight moves within 24kg and that is normal

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comment on [Discussion] can we stop arguing about regain until somebody posts a number in c/maintenancephase · 88 points · 1 year ago

Small correction: the trial was 18 weeks, not 11. Does not change your point but people will quote it.

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comment on DHL vs transit time — genuinely asking which matters more in c/intlshipping · 10 points · 1 year ago

customs clearance often adds 15 days, factor that in

Adding to this: lane is doing more work than the comment implies.

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comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago

number-needed-to-treat is the house dialect

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comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago

the discontinuation arms are the interesting part, not the STEP endpoints

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comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago

off-label use data is different from approved-indication data

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comment on someone explain carrier to me like I have not read a paper in years in c/intlshipping · 490 points · 1 year ago

Strongly agree. Customs adds unpredictable delay.

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comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 148 points · 1 year ago

the relative risk reduction in headlines is not the whole story

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