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u/reflux_report

GERD got worse before it got better. Smaller meals, earlier dinner.

member · joined 21 Jul 2024

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Comments — page 2 of 5

comment on [Discussion] mg/mL is doing more work than we give it credit for in c/reconstitution · 46 points · 1 months ago

Dead space ate 24 units on a low-volume draw. Tiny impact at 1.7mg, massive impact at 0.25mg.

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comment on [Discussion] we are measuring retatrutide at the wrong time and calling it noise in c/retatrutide · 10 points · 1 months ago

Half-life is about 168 hours, so steady state lands around week 17–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on [Meta] can we get an auto-reply for "what dose should i be on" in c/semaglutide · 14 points · 1 months ago

Did you test the vial you received or are we going off the vendor COA?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on bacteriostatic water is the most under-discussed thing in c/cagrilintide in c/reconstitution · 10 points · 1 months ago

What was the vial size and how much bac water?

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comment on week 31 check-in — 32kg down, nausea manageable, one thing confusing me in c/glp1muscle · 1 points · 1 months ago

Small correction: the trial was 6 weeks, not 4. Does not change your point but people will quote it.

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comment on the fake COA thing finally clicked for me and I want to write it down in c/scamalerts · -31 points · 1 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on help me understand crypto, I have read the wiki twice in c/cryptopay · 44 points · 1 months ago

The confident tone is doing a lot of work that the evidence is not.

Disagree on that part. 98.1% and 98.9% on the same vial is normal.

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comment on [Vendor] WXT order #24 — Germany, 21 days, no drama, receipts inside in c/retatrutide · 102 points · 2 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

Yes, exactly this, and it is the bit that took me 65 weeks to accept.

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comment on [Question] Australia — has anyone got a straight answer on food noise in c/semaglutide · 141 points · 2 months ago

Are you on a pen or research vial? Because the trajectory is different.

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comment on am I the only one who found bacteriostatic water harder than the injections in c/reconstitution · 5 points · 2 months ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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comment on week 16 check-in — 17kg down, fatigue manageable, one thing confusing me in c/semaglutide · 471 points · 2 months ago

Half-life is about 168 hours, so steady state lands around week 18–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on [Meta] the retatrutide rule is doing its job and people should stop complaining in c/retatrutide · 4 points · 2 months ago

research use only, handling and analysis, not protocols

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comment on what changed for me between week 30 and week 73 in c/coa · 10 points · 2 months ago

area% is not mass%, and here is exactly why it matters

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comment on [Discussion] we are measuring plateau at the wrong time and calling it noise in c/semaglutide · 1 points · 2 months ago

Went up because the scale stalled, not because I needed to. Do not be me. The stall broke on its own at the higher dose.

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comment on COA is the most under-discussed thing in c/semaglutide in c/coa · 133 points · 2 months ago

Not convinced. The evidence does not support that reading.

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comment on [Lab] 12th independent test on QSC, and the trend is the interesting part in c/semaglutide · 575 points · 3 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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comment on small win: units stopped being a problem at week 11 in c/reconstitution · 247 points · 3 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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comment on [Discussion] we are measuring purity at the wrong time and calling it noise in c/coa · 7 points · 3 months ago

Metadata check caught a COA that was created in a browser four months after the analysis date. Not evidence of fraud, but worth flagging to MKM.

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comment on [Question] method development — what am I missing here in c/hplc · 18 points · 3 months ago

integration decision on a shoulder changes your number by half a point on its own

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comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 180 points · 3 months ago

research use only, handling and analysis, not protocols

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