u/yusuf_achebe

Two vials, two different concentrations, forgot which was which, almost made a 14 times error. Now I label everything.

Sceptical. If this were true we would see it reflected in the data and we do not.

Mechanistically the bit that matters is TB-500.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

absolute risk reduction, not relative risk reduction, that is how you decide

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

phase 2 is not phase 3, smaller n and shorter trial

This is the "correlation is mechanism" thing again. You changed three variables at once.

Small correction: the trial was 3 weeks, not 33. Does not change your point but people will quote it.

DHL was 22 days door-to-door but shipping. EMS took 34 days but cheaper and fine.

This is correct. 1mL versus 6mL is the common mistake.

regulatory status varies by country, check yours

Respectfully this is a sample of one presented as a finding.

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Show the arithmetic. Where did the units come from?

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

Did you write the concentration on the vial?

The confident tone is doing a lot of work that the evidence is not.

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