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c/reconstitution·posted 1 months ago by u/adaeze_cabrera

[Results] 26 weeks on 5mg, full numbers, ask me anything boring

Explainer Cold Box ×5 Sourced ×3 Receipts ×3

Right, the units question again, but with numbers this time.

I have 5 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 14, not week 63. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

11,850 up / 8,725 down58% upvoted61 commentsid 14yh8713 Jun 2026

61 comments

29 in this archive, depth 5

best — the order this archive was captured in

u/ilias_steiner336 points·1 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/adaeze_cabreraOP254 points·1 months ago

This is correct. 3mL versus 14mL is the common mistake.

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u/sofia_danquah-19 points·1 months ago

stopper coring on the 2th draw because you keep using the same entry point. rotate.

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u/bac_water_banditMOD355 points·1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/liv_nkemelu220 points·1 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/vial_math_verasyringe math279 points·1 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/karim_ilunga314 points·1 months ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/yusuf_achebe149 points·1 months ago

Did you write the concentration on the vial?

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u/clara_weiss115 points·1 months ago

more water means more units for the same dose, which means finer resolution

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u/units_not_mgsyringe math57 points·1 months ago·edited

never post a calculation as advice without stating the concentration

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u/erez_perrin69 points·1 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/liv_nkemelu0 points·1 months ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/runa_grimaldi85 points·1 months ago

dead space is real and the syringe matters

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u/katrin_marchetti67 points·1 months ago·edited

show your working or it is unhelpful

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u/santiago_ndiaye24 points·1 months ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/bruno_dumitru97 points·1 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/ruben_cabrera44 points·1 months ago

Are you using a u-100 or u-40 syringe? That changes everything.

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u/honest_syringe_maybe53 points·1 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/honest_syringe_202513 points·1 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/spain_receta41 points·1 months ago

u-100 syringe, not u-40, or your math is off by factor of 19

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u/rosa_mensah26 points·1 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/emeka_delgado25 points·1 months ago
this is why i still read c/cagrilintide
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[removed]19 points·1 months ago

[removed by moderator]

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u/erez_perrin29 points·1 months ago

The single most useful thing I did was write the concentration on the vial. Stopped all the confusion after that.

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u/hub_opssite staff15 points·1 months ago

swirl, do not shake, or you are courting oxidation

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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