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c/trialwatch·posted 20 days ago by u/pancreatitis_scare

[Stats] number needed to treat, or i am not interested

Stats Sourced ×4

I have had 15 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 20 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 98.4% against a claimed 98.6%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

632 up / 143 down82% upvoted15 commentsid 11pwi810 Jul 2026

15 comments

11 in this archive, depth 4

best — the order this archive was captured in

u/slow_logbook_notes30106 points·19 days ago

What was the dropout rate?

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u/laila_almeida86 points·18 days ago

absolute risk reduction, not relative risk reduction, that is how you decide

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[deleted]56 points·18 days ago

[deleted]

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u/nils_tulloch24 points·18 days ago

give the trial name, phase, n, and primary endpoint in the body

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u/draw_up_dizzy74 points·19 days ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

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u/hub_opssite staff29 points·19 days ago

the discontinuation arms are the interesting part, not the STEP endpoints

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u/eu_apotheke_a34 points·19 days ago

off-label use data is different from approved-indication data

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u/sofia_wikstrom43 points·20 days ago

off-label use data is different from approved-indication data

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u/trialwatch_theoMOD29 points·20 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/nikhil_lindqvist20 points·19 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/yusuf_achebe6 points·19 days ago

phase 2 is not phase 3, smaller n and shorter trial

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About c/trialwatch

Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.

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