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c/bloodwork·submitted 5 months ago by u/chidi_abubakar

[Question] New Zealand — has anyone got a straight answer on lipids

Questionbranch of 5 comments

eGFR. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does. I say this having got it wrong for 4 months. My A1c was…

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5 comments, started 5 months ago
u/tidy_vialdrawer_watch9 points·5 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/chidi_abubakarOP6 points·5 months ago

My ALT went from 18 to 16 in 42 weeks. The ApoB story shows up in the trend, not the single number.

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u/milos_trevino4 points·5 months ago

Do you have baseline to compare to?

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u/gustav_cardoso8 points·5 months ago

This is correct. ApoB is the better marker.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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