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Single comment threadYou are looking at one branch of tried CagriSema for 12 weeks. here is what happened. — 27 comments in the full submission. View in context.
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c/cagrilintide·submitted 1 year ago by u/noor_vermeulen

tried CagriSema for 12 weeks. here is what happened.

Cautionbranch of 6 comments

I have had 8 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 40 days on nominally the same lane, which matters more in summer than in February. The independent number came back 96.8% against a claimed…

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This branch

6 comments, started 1 year ago
u/zeynep_zielinski61 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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[removed]23 points·1 year ago

[removed by moderator]

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u/niels_norgaard19 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/teodor_lokken33 points·1 year ago

the mechanism is different, the side effect profile reflects it

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u/titration_marshalmod · c/semaglutide16 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/throwaway_44b14 points·1 year ago

not approved anywhere, keep posts descriptive, not instructional

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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