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c/cagrilintide·submitted 8 months ago by u/aa_analysis_andy

[Discussion] the CagriSema advice in here is 14 years out of date

Discussionbranch of 4 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking cagrilintide against ApoB for 17 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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4 comments, started 8 months ago
u/ferran_halonen4 points·8 months ago

REDEFINE which arm?

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u/aa_analysis_andyOP2 points·8 months ago

REDEFINE phase 3 readouts are interesting but 3 person REDEFINE is different from 3 trial REDEFINE.

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u/noor_hovland1 point·8 months ago

REDEFINE readouts are phase 8 data

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u/wrong_network_w1 point·8 months ago·edited

the amylin agonist pool is small, community is satiety

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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