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c/cagrilintide·posted 1 year ago by u/liv_kuipers

three years of amylin threads, summarised so you do not have to read them

Trial Data

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking cagrilintide against eGFR for 29 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

0 up / 0 down48% upvoted8 commentsid 1dsvq35 Jul 2025

8 comments

8 in this archive, depth 3

best — the order this archive was captured in

u/zaid_grimaldi2 points·1 year ago

Strongly agree. REDEFINE is phase 19, not final.

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u/lane_map_larrylogistics1 point·1 year ago

Are we talking amylin or GLP-1 here?

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u/controversial_only-4 points·1 year ago

long-acting amylin is CagriSema, different satiety profile

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u/amylin_amyMOD1 point·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/viktor_erdogan1 point·1 year ago

research use only, no human protocols in posts

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[deleted]1 point·1 year ago

[deleted]

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u/emil_agyeman1 point·1 year ago

[deleted]

Yes, exactly this, and it is the bit that took me 32 weeks to accept.

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u/tove_vasquez1 point·1 year ago·edited

Strongly agree. REDEFINE is phase 23, not final.

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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