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c/cagrilintide·submitted 1 year ago by u/hplc_hobbyist

someone explain cagrilintide to me like I have not read a paper in years

Discussionbranch of 5 comments

Quick one. Canada here. CagriSema works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 4 weeks and cost roughly what I expected. The admin was worse than the…

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5 comments, started 1 year ago
u/rina_sobczak2 points·1 year ago

amylin receptor distribution is different from GLP-1

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u/hplc_hobbyistOPruns their own column2 points·1 year ago

Strongly agree. REDEFINE is phase 21, not final.

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u/teodor_lokken1 point·1 year ago

Strongly agree. REDEFINE is phase 14, not final.

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u/hana_pereira1 point·1 year ago

the co-agonism question is real and interesting

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u/incretin_ivypharmacology2 points·1 year ago

not approved anywhere, keep posts descriptive, not instructional

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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c/cagrilintide rules
  1. Amylin is not a GLP-1. Posts conflating them get corrected.
  2. CagriSema ratios in trials are fixed-dose. Do not extrapolate to self-mixing.
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