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c/cagrilintide·posted 1 year ago by u/hplc_hobbyist

someone explain cagrilintide to me like I have not read a paper in years

Discussion

Quick one. Canada here.

CagriSema works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 4 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

0 up / 0 down43% upvoted5 commentsid 1e2vbs24 Jul 2025

5 comments

5 in this archive, depth 4

best — the order this archive was captured in

u/rina_sobczak2 points·1 year ago

amylin receptor distribution is different from GLP-1

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u/hplc_hobbyistOPruns their own column2 points·1 year ago

Strongly agree. REDEFINE is phase 21, not final.

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u/teodor_lokken1 point·1 year ago

Strongly agree. REDEFINE is phase 14, not final.

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u/hana_pereira1 point·1 year ago

the co-agonism question is real and interesting

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u/incretin_ivypharmacology2 points·1 year ago

not approved anywhere, keep posts descriptive, not instructional

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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c/cagrilintide rules
  1. Amylin is not a GLP-1. Posts conflating them get corrected.
  2. CagriSema ratios in trials are fixed-dose. Do not extrapolate to self-mixing.
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