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c/cagrilintide·submitted 4 days ago by u/noor_ivaturi

[Trial Data] REDEFINE 1 — what cagri adds on top of sema

Trial Databranch of 4 comments

Genuinely asking, not being difficult. Everyone in c/reconstitution repeats that satiety is important. I believe it, but I have never seen anyone show why, and when I search I get 21 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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4 comments, started 3 days ago
u/zeynep_weiss26 points·3 days ago

CagriSema is a fixed combo in trials, not user-mixed

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u/micro_bump_mick16 points·3 days ago

This is correct. The co-agonism is real.

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u/freya_baptista13 points·3 days ago

not approved anywhere, keep posts descriptive, not instructional

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u/kavya_kravchenko10 points·3 days ago

amylin receptor distribution is different from GLP-1

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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