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c/cagrilintide·posted 6 days ago by u/forest_plot_fiona

[Caution] CagriSema trial ratios are fixed-dose, do not extrapolate to self-mixing

Caution Cold Box ×9

Right, the amylin question again, but with numbers this time.

I have 22 data points over 28 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 32, not week 81. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

1,772 up / 1,371 down56% upvoted11 commentsid g3kx2d24 Jul 2026

11 comments

2 in this archive, depth 1

best — the order this archive was captured in

u/tomas_kimani69 points·4 days ago

Crossposting this to c/labresults because the people who need it are not reading this community.

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u/lane_map_larrylogistics38 points·4 days ago·edited

CagriSema is a fixed combo in trials, not user-mixed

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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