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c/coa·submitted 1 year ago by u/anecdata_annie

is it normal to get early fullness at week 14

Labbranch of 8 comments

Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 4 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have sulphur…

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8 comments, started 1 year ago
u/coa_collectorMOD569 points·1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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u/zeynep_zielinski154 points·1 year ago

Mechanistically the bit that matters is purity. It explains most of the early profile and a decent chunk of the outcome.

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u/yusuf_nakamura195 points·1 year ago

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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u/sofia_danquah135 points·1 year ago

chromatogram or it did not happen

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u/low_appetite_lisa101 points·1 year ago

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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u/dario_boateng184 points·1 year ago

area% is not mass%, and here is exactly why it matters

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