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c/coa·submitted 1 months ago by u/india_generic_g

identity and quantity are two questions and most COAs answer one

Discussionbranch of 8 comments

Genuinely asking, not being difficult. Everyone in c/scamalerts repeats that area percent is important. I believe it, but I have never seen anyone show why, and when I search I get 13 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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8 comments, started 1 months ago
u/zaid_balogun218 points·1 months ago

Half-life is about 168 hours, so steady state lands around week 7–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/certified_referenceMOD160 points·1 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/emeka_beaulieu55 points·1 months ago

This is the correct framing. The COA structure matters as much as the number.

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u/india_generic_gOP93 points·1 months ago

The COA I was holding said 96.8% area and I thought it was trash. Turns out the method was solid and the impurity profile was clean.

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u/gallbladder_gary63 points·1 months ago

Cosigning. The batch number is load-bearing information.

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u/elodie_yilmaz53 points·1 months ago

the batch number or it did not happen

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u/bastian_moreau29 points·1 months ago

the batch number or it did not happen

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/low_appetite_lisa69 points·1 months ago

axis labels included, always

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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