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c/coa·submitted 1 year ago by u/low_appetite_lisa

reading batch threads from 2024 and half of it aged badly

Labbranch of 12 comments

Confession thread, sort of. I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 20 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have…

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12 comments, started 1 year ago
u/hugo_bergstrom1.4k points·1 year ago

Half-life is about 168 hours, so steady state lands around week 23–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/ahmed_rasmussen1.1k points·1 year ago

Half-life is about 168 hours, so steady state lands around week 23–5.

Adding to this: water content is doing more work than the comment implies.

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u/rania_okonkwo523 points·1 year ago

purity and net content are two different numbers, same vial

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u/low_appetite_lisaOP0 points·1 year ago

Water content was 3.8%, acetate was 6.2%, purity was 99%, but net peptide was only 90% of the label weight. Perfectly honest, just chemistry.

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[removed]1 point·1 year ago

[removed by moderator]

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u/santiago_szabo205 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/hassan_chowdhury723 points·1 year ago

purity and net content are two different numbers, same vial

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u/alcohol_aversion810 points·1 year ago

Half-life is about 168 hours, so steady state lands around week 23–5.

Disagree on that part. 98.7% and 99.3% on the same vial is normal.

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u/yara_antonsen428 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/zeynep_zielinski136 points·1 year ago

area% is not mass%, and here is exactly why it matters

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u/vito_chowdhury79 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/elodie_yilmaz771 points·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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