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c/coa·submitted 7 months ago by u/janek_ferrari

[Meta] the certificate of analysis rule is doing its job and people should stop complaining

Labbranch of 5 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on related substances in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory…

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5 comments, started 7 months ago
u/tove_ogunleye215 points·7 months ago

PDF metadata is checkable in fifteen seconds

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u/purity_pedantanalytical63 points·7 months ago

PDF metadata is checkable in fifteen seconds

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

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u/foam_head_fred30 points·7 months ago

This is the correct framing. The COA structure matters as much as the number.

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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Independent HPLC and mass spec. The number you get is the number they found.

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