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c/coa·posted 1 year ago by u/anya_correia

related substances is the most under-discussed thing in c/scamalerts

Lab Slow Clap ×1 Well Actually ×3

Quick one. Canada here.

purity works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 6 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

2,746 up / 951 down74% upvoted64 commentsid z4xa3v27 Mar 2025

64 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/laila_wojcik398 points·1 year ago·edited

This is the correct framing. The COA structure matters as much as the number.

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u/step_therapy_s203 points·1 year ago

post the whole document, not the headline number

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u/tomas_lehtinen-36 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/vito_chowdhury1 point·1 year ago·edited

post the whole document, not the headline number

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u/ignacio_silva1 point·1 year ago·edited

the counterion is part of the mass you paid for

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u/milos_trevino1 point·1 year ago

post the whole document, not the headline number

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u/anya_correiaOP1 point·1 year ago

What is the method line say? Not the technique, the actual method.

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[removed]1 point·1 year ago

[removed by moderator]

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u/santiago_szabo1 point·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/amira_dumitru1 point·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/milos_trevino1 point·1 year ago

area% is not mass%, and here is exactly why it matters

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u/stablecoin_steve96 points·1 year ago·edited

Cosigning. The batch number is load-bearing information.

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u/anya_correiaOP55 points·1 year ago

Sent one vial to PeptideMeter and VendorInvestigate. 93.7% and 98.6%. Cost me more than the vial did and I would do it again.

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u/bastian_moreau59 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/amira_dumitru48 points·1 year ago

Batch number and date of analysis? Both are load-bearing.

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u/yannick_haddad50 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/karma_irrelevant15 points·1 year ago

PDF metadata is checkable in fifteen seconds

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u/halima_boateng5 points·1 year ago

PDF metadata is checkable in fifteen seconds

Adding to this: area percent is doing more work than the comment implies.

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u/tidy_vialdrawer_watch37 points·1 year ago

Cosigning. The batch number is load-bearing information.

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u/dead_space_doug17 points·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/anya_correiaOP0 points·1 year ago

Metadata check caught a COA that was created in a browser four months after the analysis date. Not evidence of fraud, but worth flagging to KP.

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u/bastian_moreau10 points·1 year ago

Not to be pedantic but certificate of analysis and water content are being used interchangeably and they are not interchangeable in real life.

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u/amara_halonen6 points·1 year ago

the method line is doing real work, not just window dressing

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u/karma_irrelevant2 points·1 year ago·edited

the batch number or it did not happen

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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