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c/compounding·posted 1 months ago by u/lina_ndiaye

reading API source threads from 2024 and half of it aged badly

Discussion Slow Clap ×5

Been lurking in c/trialwatch for about 9 months and finally have something worth posting.

Short version: week 3, 2.4mg, and compounding is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 25 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 92.

793 up / 160 down83% upvoted27 commentsid 1nplty29 Jun 2026

27 comments

24 in this archive, depth 4

best — the order this archive was captured in

u/mateusz_adebayo145 points·1 months ago

Asked 13 compounders about API source. One told me, one dodged, one said they cannot say. The answer is the signal.

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[deleted]106 points·29 days ago

[deleted]

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u/jonas_eriksen52 points·29 days ago

Yeah, 503A and 503B are different regulatory animals.

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u/naomi_erdogan112 points·1 months ago·edited

Asked 13 compounders about API source.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/escrow_evangelist65 points·29 days ago·edited

state board rules differ, say which state

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u/eu_apotheke_a33 points·29 days ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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u/quiet_moderatorMOD102 points·1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/rafael_ostergaard84 points·29 days ago

regulatory claims need a citation to the actual rule, not interpretation

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u/slow_logbook-34 points·29 days ago

Strongly agree. API source transparency matters.

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u/maren_sorensen106 points·29 days ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/camila_sandvik60 points·1 months ago

Yeah, 503A and 503B are different regulatory animals.

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u/quiet_moderatormod87 points·1 months ago

Strongly agree. API source transparency matters.

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u/escrow_evangelist33 points·29 days ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/lina_ndiayeOP44 points·1 months ago

Respectfully this is a sample of one presented as a finding.

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u/ruben_cabrera21 points·29 days ago

the Sweden situation is different from the US, different regulations

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u/lina_ndiayeOP15 points·29 days ago

The telehealth + compounding combo cost API source plus 21% markup. Not cheap but covered by insurance depending on state.

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u/zaid_grimaldi32 points·29 days ago

Not convinced. The evidence does not support that reading.

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u/food_noise_gonemaintenance15 points·29 days ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/nadia_fonseca46 points·29 days ago

Slight fix: the number was 93.7, not 99.3. Decimal point, but a fairly consequential one.

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u/lipid_panel_larrybloodwork37 points·29 days ago·edited

Strongly agree. API source transparency matters.

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u/escrow_evangelist11 points·29 days ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/clara_danquah2 points·29 days ago

the 503A/503B distinction is load-bearing, do not blur it

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u/escrow_evangelist1 point·28 days ago·edited

API source questions are on-topic and compounders dodging them is newsworthy

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u/milos_mensa26 points·1 months ago

The telehealth + compounding combo cost telehealth plus 12% markup. Not cheap but covered by insurance depending on state.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
  2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
  3. API source questions are on-topic and pharmacies dodging them is newsworthy.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
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