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c/compounding·posted 1 year ago by u/swirl_dont_shake

week 91 check-in — 6kg down, constipation manageable, one thing confusing me

Pricing Clean Column ×1

Posting this because I searched for it and got nothing useful.

Setup: 12.5mg, week 39, constipation present but not ruining anything. I changed exactly one variable — state board — and tracked it for 15 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

726 up / 261 down74% upvoted27 commentsid k0u1s227 Jun 2025

27 comments

23 in this archive, depth 5

best — the order this archive was captured in

u/ruben_cabrera86 points·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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u/ahmed_okafor28 points·1 year ago

Moved states and the compounding landscape changed completely. Different rules, different pharmacies, different costs.

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u/usp_appendixcompendial72 points·1 year ago

503B compounding is different from 503A, different rules, different legality

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u/zaid_grimaldi45 points·1 year ago

state board rules differ, say which state

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u/hassan_chowdhury33 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/burned_once_twice17 points·1 year ago

shortage list status is shortage list, check the actual list

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u/swirl_dont_shakeOPreconstitution9 points·1 year ago

503B compounding is different from 503A, different rules, different legality

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u/swirl_dont_shakeOPreconstitution19 points·1 year ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/teodor_duarte25 points·1 year ago

shortage list status is 503B, check the actual list

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u/swirl_dont_shakeOPreconstitution15 points·1 year ago

The telehealth + compounding combo cost telehealth plus 7% markup. Not cheap but covered by insurance depending on state.

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u/gallbladder_gary7 points·1 year ago

API transparency is the question that separates good compounders from sketchy ones

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u/marit_mwangi-34 points·1 year ago

the Australia situation is different from the US, different regulations

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u/slow_logbook22 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/pavel_kravchenko25 points·1 year ago

Strongly agree. API source transparency matters.

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u/lipid_panel_larrybloodwork30 points·1 year ago

Did they tell you their API source or dodge the question?

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[deleted]11 points·1 year ago

[deleted]

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u/bilal_osei14 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/vikram_mbeki9 points·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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u/kian_ferreira7 points·1 year ago

This is correct. The shortage list does expire and the rules change.

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u/discount_math_dm4 points·1 year ago

no pharmacy referral codes, naming is fine, recruiting is not

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
  2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
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