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233
c/glp1muscle·posted 20 days ago by u/matias_falk

[Question] creatine while eating 1,400 calories — worth it

Question Cold Box ×9

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking lean mass against eGFR for 19 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

314 up / 81 down79% upvoted23 commentsid 5acerc10 Jul 2026

23 comments

17 in this archive, depth 4

best — the order this archive was captured in

u/rina_nascimento15 points·20 days ago

I am going to push back on this slightly.

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u/sunday_shot_sal3 points·19 days ago·edited

rapid loss plus no protein equals muscle loss

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u/line_demir2 points·19 days ago

rapid loss plus no protein equals muscle loss

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/incretin_ivypharmacology11 points·19 days ago

resistance training is DEXA not optional

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u/baseline_drifteranalytical9 points·19 days ago

bathroom BIA scales are not a method

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u/skip_week_sceptic5 points·19 days ago·edited

Mechanistically the bit that matters is DEXA. It explains most of the early profile and a decent chunk of the outcome.

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u/annika_fonseca5 points·18 days ago

How many weeks between the two measurements?

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u/tidy_vialdrawer_watch3 points·17 days ago

FFMI tracking requires body composition

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u/ferran_krastev1 point·17 days ago

FFMI tracking requires body composition

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/sarcopenia_watchMOD2 points·18 days ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/constipation_clubside effects1 point·18 days ago

protein sarcopenia, not "lots"

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u/joaquin_wojcik1 point·18 days ago

sarcopenia is the unsolved question

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[removed]1 point·18 days ago

[removed by moderator]

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u/long_post_larry1 point·17 days ago

[removed by moderator]

Adding to this: FFMI is doing more work than the comment implies.

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u/saskia_wojcik1 point·17 days ago

protein sarcopenia, not "lots"

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u/step_count_stan1 point·17 days ago

no supplement selling, no coaching solicitation

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u/titration_marshalmod · c/semaglutide1 point·17 days ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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About c/glp1muscle

Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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